Product Overview

Susten 8% Vaginal Gel is a pharmaceutically formulated progesterone preparation manufactured by Sun Pharmaceutical Industries Ltd. The gel is supplied in a single-use tube containing 8% progesterone, indicated for female infertility and hormone replacement therapy. Each package includes one vaginal gel unit; bulk options are available in 12, 6, or 3 gel units per pack.

What is Susten 8% Vaginal Gel?

Susten is a brand of progesterone designed for vaginal administration. The 8% concentration provides a controlled release of the hormone directly into the uterus, supporting the luteal phase and improving implantation chances. It is classified under female infertility treatments and also used in hormone replacement protocols for menopausal symptoms.

Uses and Benefits

This gel is prescribed to:

• Enhance endometrial receptivity in assisted reproductive technology (ART) cycles.
• Support luteal phase deficiency in women attempting conception.
• Provide systemic hormone replacement for low progesterone levels.
• Reduce the risk of miscarriage associated with insufficient progesterone.

Clinical studies cited by the National Center for Biotechnology Information demonstrate improved pregnancy rates when progesterone gel is used in IVF protocols.

How It Works

Progesterone exerts its effect by binding to intracellular progesterone receptors, modulating gene expression that prepares the endometrium for implantation. The gel formulation ensures steady local concentrations, minimizing peaks and troughs that can occur with oral administration.

Dosage Guidelines

Typical dosing is one tube (approximately 8 mg of progesterone) administered vaginally once daily, preferably at bedtime, for up to 12 weeks of gestation or as directed by a physician. Dosage may be adjusted based on serum progesterone levels and clinical response. Patients should follow the prescribing information carefully and not exceed the recommended duration without medical supervision.

Side Effects

Most users experience mild, transient reactions such as vaginal discharge, irritation, or spotting. Rarely, systemic absorption can cause dizziness, abdominal cramping, or breast tenderness. If severe allergic reactions occur, discontinue use and seek immediate medical attention.

Warnings and Precautions

Do not use if you have a known hypersensitivity to progesterone or any excipients. Patients with active thromboembolic disorders, liver disease, or unexplained vaginal bleeding should consult a healthcare provider before initiating therapy. This product is for adult women only; pediatric use is not established.

Frequently Asked Questions

1. What is the strength of Susten vaginal gel? The gel contains 8% progesterone by weight, delivering approximately 8 mg of active hormone per tube.
2. How long does shipping take? Delivery typically requires 6 to 15 days from the date of order, depending on the destination.
3. Can Susten be used alongside other fertility medications? Yes, it is often combined with ovulation induction agents, but coordination with a reproductive endocrinologist is recommended.
4. Is this product FDA approved? Susten is manufactured under FDA‑compliant facilities and meets all regulatory standards for pharmaceutical quality.
5. Are there any lifestyle restrictions while using the gel? Patients should avoid douching or using intravaginal contraceptives during treatment to prevent interference with absorption.

For additional information, refer to the U.S. Food and Drug Administration and MedlinePlus resources.

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